Applications

Making a Tethered Bilayer

1. Starter kit to study tethered membranes.

1.  Starter kit to study tethered membranes.

2. To make a tethered membrane bilayer with Starter Kit.

2. To make a tethered membrane bilayer with Starter Kit.

Membrane Biophysics

3. Micelles or bilayers?

3. Micelles or bilayers?

4. Micelles to bilayers.

4. Micelles to bilayers.

5. Determine partition coefficients.

5. Determine partition coefficients.

Ion Channels

6. Peptide ion channels.

6. Peptide ion channels.

7. Change percentage of tethered lipids to accommodate Ion Channels

7. Change percentage of tethered lipids  to accommodate Ion Channels

8. Many approaches to incorporating Ion Channels into tethered membrane

8. Insertion of purified ion channel proteins

9. Kinetics of insertion, formation or switching of channels.

9. Kinetics of insertion, formation or switching of channels.

10. Aggregation state - Dimers, tetramers ...?

10. Aggregation state for ion channels.

11. Species dependent ion conduction

11. Species dependent ion conductione

12. Voltage dependence of channels.

12. Voltage dependence of channels.

Screening

13. Screen for ion channel blockers.

13. Screen for ion channel blockers.

14. Grow cells and measure activity through local ion flux

14. Screen cell activity

Measurement

15. Ion channel switch demonstrator

15. Ion channel switch demonstrator

16. Ion channel switch detector

16. Ion channel switch detector

17. Ion selective electrode

17. Ion selective electrode